|
|
S-adenosyl-L-methionine + (S)-3''-hydroxy-N-methylcoclaurine <=> H+ + S-adenosyl-L-homocysteine + (S)-reticuline
|
2.1.1.116
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase
2.1.1.128
(RS)-norcoclaurine 6-O-methyltransferase
|
–
–
|
MK
|
| |
BRENDA:
BR1437
KEGG:
R03832
MetaCyc:
2.1.1.116-RXN
|
|
|
|
O2 + (S)-reticuline <=> H+ + H2O2 + (S)-scoulerine
|
1.21.3.3
reticuline oxidase
|
–
|
MK
|
| |
BRENDA:
BR36965
KEGG:
R03831
MetaCyc:
RETICULINE-OXIDASE-RXN
|
|
|
|
S-adenosyl-L-methionine + (S)-reticuline <=> H+ + (S)-laudanine + S-adenosyl-L-homocysteine
|
2.1.1.291
(R,S)-reticuline 7-O-methyltransferase
|
–
|
M
|
| |
BRENDA:
BR50637
KEGG:
R10605
MetaCyc:
RXN-8700
|
|
|
|
S-adenosyl-L-methionine + (S)-reticuline <=> S-adenosyl-L-homocysteine + (S)-tembetarine + H+
|
2.1.1.337
reticuline N-methyltransferase
|
–
|
|
| |
BRENDA:
BR51954
KEGG:
R11595
MetaCyc:
RXN-18426
|
|
|
|
(S)-reticuline + reduced_flavodoxin + O2 <=> (S)-corytuberine + flavin + 2 H2O
|
1.14.19.51
(S)-corytuberine synthase
|
–
|
K
|
| |
BRENDA:
BR52042
KEGG:
R08790
|
|
|
|
(S)-reticuline + reduced_flavodoxin + O2 <=> 1,2-dehydroreticuline + flavin + 2 H2O
|
1.14.19.54
1,2-dehydroreticuline synthase
|
–
|
K
|
| |
BRENDA:
BR52350
KEGG:
R03833
|
|
|
|
(S)-reticuline + S-adenosyl-L-methionine <=> laudanine + S-adenosyl-L-homocysteine
|
2.1.1.291
(R,S)-reticuline 7-O-methyltransferase
|
–
|
K
|
| |
KEGG:
R08787;
R08788
SABIO-RK:
12709;
12710
|
|
|
|
S-adenosyl-L-methionine + (S)-norreticuline <=> S-adenosyl-L-homocysteine + (S)-reticuline
|
2.1.1.115
(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase
|
–
|
K
|
| |
KEGG:
R05211
|
|
|
|
(S)-reticuline <=> (S)-Isoboldine
|
not assigned
|
–
|
|
| |
KEGG:
R08460
|
|
|
|
(S)-reticuline + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1,2-dehydroreticuline + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.54
1,2-dehydroreticuline synthase
|
–
|
M
|
| |
MetaCyc:
RXN-8142
|
|
|
|
(S)-reticuline + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (S)-corytuberine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.51
(S)-corytuberine synthase
|
–
|
M
|
| |
MetaCyc:
RXN-9314
|
|
|
|
S-adenosyl-L-methionine + (S)-Norlaudanosoline <=> H+ + (S)-reticuline + S-adenosyl-L-homocysteine
|
not assigned
|
–
|
M
|
| |
MetaCyc:
RXN-9981
|
|
|
|
(S)-reticuline + O2 <=> dehydroscoulerine + H2O2
|
1.21.3.3
reticuline oxidase
|
–
|
|
| |
BRENDA:
BS403157
|
|
|
|
S-adenosyl-L-methionine + (S)-reticuline <=> S-adenosyl-L-homocysteine + codamine + laudanine
|
2.1.1.117
(S)-scoulerine 9-O-methyltransferase
|
–
|
|
| |
BRENDA:
BS456366
|
|
|
|
S-adenosyl-L-methionine + (S)-reticuline <=> S-adenosyl-L-homocysteine + (S)-tetrahydropapaverine
|
2.1.1.300
pavine N-methyltransferase
|
–
|
|
| |
BRENDA:
BS456365
|
|
